About
Human albumin to treat B cell dysfunction in decompensated cirrhosis and sepsis. An investigation to assess dosage, biomarkers of immune response, and further insights on pathophysiology.
- Open label, randomized clinical trial
- 150 patients
- 11 sites
Description
To assess the dose effect of albumin treatment on B cell and neutrophil function in three groups of subjects:
Healthy subjects
Patients with decompensated cirrhossis without indication for albumin therapy
Non-cirrhotic patients hospitalized with sepsis
Centers
Barcelona, Spain
- Hospital Clínic de Barcelona
- Hospital de la Santa Creu i Sant Pau
- Hospital del Mar
- Hospital Germans Trias i Pujol
- Hospital Universitari Vall d’Hebron
Madrid, Spain
- Hospital Gregorio Marañón
- Hospital Universitario Ramón y Cajal
Sabadell, Spain
- Hospital Universitari Parc Taulí de Sabadell
Brussels, Belgium
- CUB Hôpital Erasme
Münster, Germany
- Uniklinik Münster
Padua, Italy
- Azienda Ospedale Università Padova